Choleretic Drugs For Stagnation Of Bile In The Gallbladder

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Video: Choleretic Drugs For Stagnation Of Bile In The Gallbladder

Video: Choleretic Drugs For Stagnation Of Bile In The Gallbladder
Video: Bile Sludge Is a Pre-Gallstone Condition 2023, September
Choleretic Drugs For Stagnation Of Bile In The Gallbladder
Choleretic Drugs For Stagnation Of Bile In The Gallbladder
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List of choleretic drugs for bile stasis

List of choleretic drugs
List of choleretic drugs

Diseases of the gallbladder are common. Among them, biliary dyskinesia and cholecystitis, all of them are often accompanied by chronic pancreatitis. Moreover, not only adults, but also children are sick. Symptoms of the pathology are not always obvious: a decrease in appetite, mild nausea in the morning hours, pain in the right hypochondrium and skin itching are possible. However, a person without medical education does not always manage to independently associate these signs of ill health with bile stagnation. While even a slight delay in the diagnosis and treatment of the disease can be dangerous and lead to the formation of stones. To prevent this from happening, it is necessary to take choleretic drugs. It is these drugs that our article is devoted to.

Content:

  • Bile stagnation - what is it?
  • Indications for taking choleretic drugs
  • List of choleretic drugs for choleretics
  • List of cholekinetics
  • List of cholespasmolytics
  • List of cholelitis
  • Choleretic herbal preparations
  • Choleretic drugs for the treatment of children
  • The best choleretic drugs

Bile stagnation - what is it?

Stagnation of bile
Stagnation of bile

Some patients are firmly convinced that bile is produced and stagnant in the gallbladder. In fact, this is not entirely true. Bile is produced by hepatocytes, which are liver cells. From the liver, bile enters the gallbladder, where it reaches the concentration it needs by getting rid of excess water.

Bile comes out of the gallbladder at the moment when food containing fats enters the human stomach. The organ begins to contract and through the bile ducts, bile enters the duodenum. The opening through which it exits is located in the immediate vicinity of the opening through which the pancreas throws out its enzymatic secretion into the duodenum.

Bile is necessary for the body to solve the following tasks:

  • Bile dilutes fats to an emulsion, which facilitates the "work" of the enzymatic mixture. This fraction will be much easier for enzymes to dissolve.
  • Bile provides the normal working conditions for pancreatic enzymes. Otherwise, they could not fully dissolve food into essential nutrients.
  • Bile causes the intestines to contract.
  • Bile enables the absorption of vitamins A, D, E and K, which are fat-soluble.
  • Bile prevents pathogenic microorganisms from entering the bloodstream. It simply does not allow them to attach to the intestinal walls, and they cannot be absorbed as well as food.
  • Bile helps to remove cholesterol, bilirubin and some hormones from the body. They pass through the liver and are excreted through bile along with feces.

Therefore, there is no reason to doubt the benefits of bile. However, in order for it to fully perform all its functions, it is necessary to provide conditions for its adequate education and admission to the duodenum. If the body is unable to cope with this task, then choleretic drugs come to its aid. However, this does not mean that you can take all medicines indiscriminately.

There are 4 groups of choleretic drugs.

Each group has specific goals and objectives:

  1. Group 1: choleretics. These drugs are aimed at increasing bile production.
  2. Group 2: cholekinetics. They accelerate the excretion of bile from the liver ducts, so it reaches the duodenum more quickly.
  3. Group 3: cholespasmolytics. These drugs relieve spasm from the bile ducts.
  4. Group 4: cholelitogenic preparations of bile acids. They are necessary in order to dilute too concentrated bile and prevent stones from forming in it. Also, drugs from this group ensure the dissolution of small stones, which occurs by changing the properties of bile.

To choose one or another remedy, you need to know which process in the body is disturbed. Unjustified intake of choleretic drugs can only aggravate the situation. For example, why relieve a spasm from the bile ducts if they are in a relaxed state or force the diseased liver to produce more bile when it is already working "to wear and tear."

Indications for taking choleretic drugs

Indications for taking choleretic drugs
Indications for taking choleretic drugs

To understand which drug to choose and take, it is necessary to understand the direction of movement of bile through the body.

Her path is as follows:

  • Bile is formed in the cells of the liver, after which it enters the intrahepatic bile ducts.
  • Through the intrahepatic pathways, bile enters the hepatic ducts (left and right). From them, it flows into the common hepatic duct, represented by a tube, containing a minimum amount of muscles.
  • From this duct, bile enters the gallbladder through another duct, which is unable to contract, since it does not have a muscular base. It takes some strength to pour into your storage tank (gallbladder). The difference in pressure acts as it: the pressure of the liver, when it produced bile, against the resistance of the sphincter of Oddi. This sphincter is represented by the round muscle, which is a continuation of the common hepatic duct. It leads into the duodenum. The sphincter of Oddi can be compared to a tap: if it is closed, then bile enters the cystic duct, straightens the muscleless folds and enters the gallbladder, where it begins to heat up.

  • When the gallbladder fills with bile, pressure builds up in it. At the same time, it decreases in the hepatic tract. If food enters a person's stomach, it begins to produce pepsin, which signals the sphincter of Oddi to open. Due to pressure drops, bile enters the duodenum, having the desired concentration, which it acquired in the gallbladder, getting rid of excess fluid.
  • When the pressure in the gallbladder rises to 250-300 mm of water column, the organ begins to contract on its own, which forces the sphincter of Oddi to open.
  • The common bile duct is deprived of the ability to contract, since it practically does not have muscle fibers.

Knowing which path bile makes in the human body, you can understand the question of choosing a medicine.

Indication number 1: biliary dyskinesia

biliary dyskinesia
biliary dyskinesia

Dyskinesia means that bile moves with impairments, but which ones need to be dealt with.

Dyskinesia depends on several parameters:

  • Biliary tract tone. If it is normal, then no medications need to be taken. If the tone is increased, then bile will exit from the biliary tract too quickly, which will lead to its throwing into the stomach. In this case, it is required to take drugs from the group of cholespasmolytics. When the tone of the biliary tract is too low, then bile will move slowly along them. Cholekinetic preparations are used to raise the tone.
  • The rate of contraction of the biliary tract. If they contract at a normal rate, then no treatment is required. At a high rate of contraction, bile does not have time to gain the concentration it needs. To correct this condition, you will need to take antispasmodics. If the bile ducts, on the other hand, contract too slowly, then bile will stagnate. In this case, a person needs to take either choleretics (more bile will be formed), or cholekinetics, which accelerate its movement.

So, a more accurate diagnosis of "biliary dyskinesia" can be as follows:

  • Hypertensive hyperkinetic dyskinesia. Most often, synthetic cholespasmolytics are prescribed.
  • Hypertensive normokinetic dyskinesia. In this case, the patient is prescribed cholespasmolytics of plant origin, which do not reduce the contractility of the biliary tract.
  • Hypertensive hypokinetic dyskinesia. In this case, bile cannot pass along the pathways due to their spasm, so it must be eliminated. In combination with an antispasmodic, cholekinetics are prescribed.
  • Hypotonic hypokinetic dyskinesia. To get rid of pathology, cholekinetics and choleretics are needed.
  • Hypotonic normokinetic dyskinesia. To eliminate this violation, a choleretic is required.

If you take drugs without understanding what is happening with bile in the body, then serious health problems can arise. Most people take choleretics, which stimulate bile production. At the same time, they do not think about the consequences. After all, the likelihood of an inflection of the gallbladder or hypokinetic dyskinesia cannot be ruled out. An excess of bile will cause the gallbladder to contract very sharply, which causes severe pain. This pain is known as bilious colic.

In addition, a person can take cholespasmolytics. This will lead to stagnation of bile, in which salts will begin to accumulate in conjunction with cholesterol. Then they will precipitate, which will provoke the formation of stones. Also, infection of bile with the further development of cholecystitis cannot be ruled out.

Indication number 2: stagnation of bile

The drugs that are prescribed to eliminate stagnation belong to the group of cholekinetics and choleretics. However, before taking them, it is necessary to undergo an ultrasound scan to make sure there are no stones in the bile ducts. When such deposits are absent, or their diameter does not exceed 3 mm, then the patient is prescribed drugs based on bile acids.

When bile stagnates in the liver and the patient develops pruritus, and the dermis itself acquires a yellow tint, choleretic drugs are required in combination with other drugs. Treatment at home is often impractical and the patient is hospitalized.

Indication number 3: kink of the gallbladder

When the gallbladder is bent, dyskinesia always develops. It can be hypokinetic and hypermotor. To eliminate this violation, you will need cholespasmolytics, cholekinetics, as well as agents containing bile acids. If the pathology is not in an acute stage, then the choice should be stopped on herbal remedies.

It also cannot be ruled out that the kink of the gallbladder is characterized by hypomotor and hypokinetic dyskinesia. In this case, the patient is prescribed drugs from the cholekinetic group. Although sometimes they are replaced by taking choleretics.

Indication number 4: cholecystitis

cholecystitis
cholecystitis

Cholecystitis is an inflammation of the gallbladder itself.

To eliminate it, the following drugs are used:

  • Choleretics that thin bile, freeing it from infection. Thus, it seems to be possible to refresh it.

  • Cholespasmolytics, which reduce the intensity of pain and relieve spasm from the muscle wall of the gallbladder.
  • Cholelitogenic drugs that are used to prevent the formation of gallstones.

To eliminate inflammation, antibacterial drugs are required. Moreover, it is recommended to use antibiotics of different group accessories (2 drugs).

Indication number 4: pancreatitis

Inflammation of the pancreas, called pancreatitis, causes the enzymatic secretion to be produced in large volumes. Bile stimulates the production of these enzymes, so in order not to aggravate the situation, you need to make sure that it is released little by little. You should also exclude the possibility of an unexpected release of bile. For this purpose, cholespasmolytics are prescribed. Their use is indicated for both chronic and acute pancreatitis. To prevent stones from forming in the gallbladder during this period (stagnation cannot be avoided), you need to take drugs in parallel to dissolve them.

It is important to understand that inflammation of the pancreas is a serious pathology that requires medical supervision.

Indication number 5: removal of the gallbladder

gallbladder removal
gallbladder removal

After the gallbladder is removed from the body, bile loses the place where it could reach the concentration it needs. As a result, it enters the duodenum in a diluted form. However, stones can form even in such a low-concentration liquid. Therefore, all patients without exception are prescribed cholelitogenic drugs.

It is strictly forbidden to take choleretics after the operation, as this will lead to an increase in the production of bile.

For a period of 3 months (after undergoing cholecystectomy), patients are prescribed antispasmodics. The fact is that when the gallbladder was still present in the body, it worked with the sphincter of Oddi in pairs. The bladder contracted, and the sphincter relaxed. After the organ is removed, the sphincter of Oddi is not able to do its job as consistently as before. Therefore, his muscles are simply spasmed. To relieve this spasm, you must take cholespasmolytics. If this is not done, then the spasm will turn into stenosis and the person will return to the surgical table.

Hypertonicity of the sphincter of Oddi requires the use of cholekinetics. In parallel, the patient should receive antibiotics, anti-inflammatory drugs and hepatoprotectors.

List of choleretic drugs for choleretics

List of choleretic drugs for choleretics
List of choleretic drugs for choleretics

All choleretics are divided into 2 types:

  1. True choleretics. They increase the volume of bile by stimulating its production in the liver. Depending on what kind of substance is the basis of the drug, the following subspecies of true choleretics are distinguished:

    • Bile acid preparations. They are obtained from the bile of animals.
    • Preparations of synthetic origin, which are aimed at stimulating the formation of bile.
    • Preparations based on herbal raw materials that activate the processes leading to the production of bile.
  2. Hydrocholeretics. These drugs are aimed at increasing the volume of the gallbladder, as they dilute it with water.

Below will be presented preparations of exclusively synthetic or animal origin, as well as hydrocholeretics. Herbal medicines are listed under a separate heading.

Allohol

Allohol
Allohol

The drug is based on natural bile, it is also supplemented with such components as activated charcoal, garlic and nettle. Alternatively, such agents can be used as: Cholenzym (this drug has an addition in the form of enzymes), Festal (its composition is similar to that of Cholenzyme) and Medical bile in the form of an emulsion.

It is not always possible to use Allochol, it is not prescribed for exacerbation of hepatitis, and Festal and Holenzym are not taken against the background of inflammation of the pancreas, with mechanical blockage of the biliary tract, as well as against the background of dystrophic changes in the liver tissues.

Allochol has several advantages. The drug allows you to cleanse the liver, removes toxins from the body, quickly relieves the symptoms of dyskinesia. Allochol has been used as a medicine for many decades, so all of its properties are thoroughly known to medicine. Allohol has been produced since 1964 and is the development of domestic specialists. This leads to a low cost of the drug and protection against counterfeiting. Allochol is an extremely successful composition of plant and animal components, which allows solving many problems of the hepatobiliary system. In addition, the drug can be combined with other drugs, for example, antiseptics, vitamins, laxatives. In addition to achieving a choleretic effect, Allochol is taken to prevent the formation of stones in the bile ducts.

As for the cons of Allohol, they boil down to the fact that this drug still has a number of contraindications. This is primarily true for acute inflammation of the digestive system.

Price for the drug: from 10 to 60 rubles.

Odeston

Odeston
Odeston

Odeston is based on Hymecromone. This substance is of synthetic origin. The analogues of this drug are drugs called Cholestil and Holonerton, but they are not yet on sale, since they are undergoing appropriate registration.

Odeston is not prescribed for blockage of the biliary tract, with Crohn's disease, against the background of increased bleeding of the gums and gastric ulcer. You can not take Odeston for serious kidney problems, as well as during breastfeeding.

The main advantage of the drug is that it has a double effect, that is, it acts as a choleretic drug (eliminates heaviness and pain in the right hypochondrium, relieves the taste of bitterness in the mouth, from nausea) and as an antispasmodic agent (relaxes the bile ducts and the sphincter Oddi). Odeston is available over the counter without a prescription.

As for the disadvantages of the drug, they include the presence of contraindications, in which the drug is prohibited to take. While biliary dyskinesia is often combined with various pathologies of the digestive system. Also, the disadvantages of Odeston include its high cost, which varies from 360 to 750 rubles, depending on the number of tablets in the package.

Nikodin

Nikodin
Nikodin

This is a drug based on a synthetic substance called gimecromone. Similar drugs are Cholestil and Holonerton.

Nikodin is not prescribed for blockage of the bile ducts, for gastritis with low acidity of gastric juice.

The advantage of the drug Nikodin is its pronounced choleretic effect. In addition, it has antimicrobial and bactericidal action, therefore it is prescribed for inflammation of the gallbladder. This means that Nikodin not only eliminates the symptoms of the disease, but also treats it.

At the moment, this drug is at the stage of re-registration, so its cost is unknown. This is the most significant drawback of the drug. In addition, it is not prescribed for the treatment of pregnant women and children under 10 years of age.

In addition to the listed medicines, mineral waters that have an alkaline environment can be considered hydrocholeretics, among them:

  • Borjomi.
  • Slavyanovskaya.
  • Essentuki numbered 4 and 17.
  • Jermuk.
  • Naftusya.

List of choleretic drugs cholekinetics

These medicines help to shrink the biliary tract. These include:

Magnesium sulfate powder

Magnesium sulfate
Magnesium sulfate

The preparation contains pure magnesium. Other drugs containing magnesium are analogous.

For treatment, it is necessary to dissolve 1 sachet in a liter of water and take this solution a tablespoon 3 times a day.

Magnesium is not used for allergic reactions, as well as against the background of inflammatory processes in the intestines. Also, magnesium is not prescribed for cholelithiasis, during pregnancy and with obstruction of the pathways for the outflow of bile.

The advantages of the drug include its low cost, which is 30 rubles, as well as ease of use.

The disadvantage of the drug is that it cannot be taken if there are gallstones. Therefore, without passing a medical examination, the use of the drug is unacceptable.

Sorbitol

Sorbitol
Sorbitol

Sorbitol acts as the main active ingredient. The drug has no analogues. To provide a therapeutic effect, a tablespoon of Sorbitol is dissolved in 250 ml of warm water and taken orally. Then it is necessary to place a warm heating pad under the right hypochondrium and lie in this position for half an hour.

You can not take the drug with ascites, with irritable bowel syndrome, with inflammation of this organ.

The advantages of the drug include its rapid therapeutic effect, as well as its low cost. For 350 g of powder, you will have to pay no more than 90 rubles.

The disadvantage of the drug is that it can provoke flatulence and diarrhea. If sorbitol is taken in large quantities, then this is associated with the risk of developing diabetic retinopathy and neuropathy. Moreover, it is contraindicated in obese patients.

List of cholespasmolytic drugs

Medicines in this group are:

Bellalgin

Bellalgin
Bellalgin

The drug contains belladonna extract, metamizole, soda and benzocaine. A similar preparation containing belladonna extract is Atropine.

Bellalgin can cause serious side effects, so it is prescribed solely on medical advice. Most often, the patient is prescribed one tablet 2-3 times a day.

You can not take Bellalgin during pregnancy, against the background of tachycardia, with glaucoma, with impaired liver and kidney function, against the background of impaired blood formation.

The obvious advantage of the drug is its low cost. For a package of 10 tablets, you will need to pay 60 rubles. In addition to the fact that it has an antispasmodic effect, the drug helps to eliminate pain.

The disadvantages of the drug include its multiple contraindications and side effects. Despite the fact that Bellalgin has an analgesic effect, it should not be taken for acute pain until the cause has been established.

Metacin

Metacin
Metacin

The basis of the drug is a substance called methocinium iodide. Metacin has no analogues. As a rule, patients are prescribed 1-2 tablets, 2-3 times a day.

You can not take the drug for diseases of the cardiovascular system, with reflux esophagitis, with a hernia of the diaphragm, against the background of renal and hepatic failure.

The obvious advantage of the drug is that it can be prescribed for the treatment of pregnant women and children. In addition, Metacin has a pronounced analgesic effect, therefore it is allowed to use it to relieve renal colic. The price of the drug is not high and is within 180 rubles.

The disadvantage of the drug is the presence of side effects, and quite serious, for example, accommodation paralysis, urinary retention and increased intraocular pressure.

Platyphyllin

Platyphyllin
Platyphyllin

The main active ingredient is platyphylline hydrotartrate. The drug has no analogues. It can only be used as a subcutaneous injection.

Do not prescribe Platyphyllin to patients with atherosclerosis, heart disease, diaphragmatic hernia, as well as bleeding from the stomach or intestines.

The advantages of the drug include its low cost (70 rubles will have to be paid for 10 ampoules), rapid elimination of pain and spasm. Also, this one is time-tested.

As for the disadvantages of Platyphyllin, they include soreness at the site of its introduction. There is no possibility of oral administration, since the drug is released only in the form of a solution for making an injection.

Papazol

Papazol
Papazol

Papazol is a drug based on papaverine hydrochloride and bendazole. Similar drugs include Dibazol, Papaverine in suppositories and injections.

Take Papazol one tablet 2 or 3 times a day.

You can not use the drug to treat patients with low blood pressure, as well as in the elderly.

The advantages of the drug include its extremely low cost (10 rubles per package containing 10 tablets), as well as the combined effect. In addition to the antispasmodic effect, Papazol is able to stimulate the immune system, lower blood pressure and relax the vascular walls in hypertonicity.

The disadvantages of the drug can be considered the presence of contraindications and side effects. It is not prescribed for patients with renal failure. In addition, Papazol is capable of interacting with many drugs, so only a doctor can recommend its use.

Drotaverin

Drotaverin
Drotaverin

The main active ingredient is drotaverine. An analogue of this drug is No-shpa.

Take the drug 1-2 tablets no more than three times a day. Drotaverin should not be prescribed to patients suffering from atherosclerosis and glaucoma.

Drotaverin is an inexpensive drug of domestic origin, its cost does not exceed 70 rubles per package. Also, the advantage of the drug is its speed, the duration of the analgesic effect and high bioavailability, which is equal to 100%.

As for the disadvantages of Drotaverin, they include only the side effects that it can give. First of all, this concerns a sharp decrease in blood pressure and depression of the respiratory center. In childhood, the drug can only be used in tablet form.

Duspatalin

Duspatalin
Duspatalin

The main active ingredient is mebeverine. An analogue of Duspatalin is Mebeverin. It is taken one capsule twice a day.

Do not prescribe the drug to children under 10 years of age, as well as to pregnant women.

As for the advantages of the drug, they include the rapid removal of spasm and targeted exposure. It is permissible to take Duspatalin for two weeks without consulting a specialist, but on condition that the person has no contraindications to it.

The disadvantages of the drug include its high cost and the presence of side effects. For packaging, you will need to pay from 510 to 600 rubles.

Euphyllin

Euphyllin
Euphyllin

The main active ingredient is aminophylline. The analogue of Euphyllin, the drug Aminophylline, is currently being re-registered.

Patients are prescribed Euphyllin 1 tablet 3 times a day.

You can not use the drug against the background of myocardial infarction, with arrhythmias and other heart diseases. It is not prescribed for acute stomach ulcers. It is also contraindicated in children under 6 years of age, in patients with epilepsy and hyperthyroidism.

Euphyllin's price is low and amounts to 20 rubles. Also, the advantages of the drug include its speed and a small number of side effects.

The disadvantage of the drug is the presence of contraindications, which are mainly associated with diseases of the cardiovascular system. Therefore, most cardiac patients simply will not be able to use Euphyllin to relieve spasm and pain.

Galidor

Galidor
Galidor

The main active ingredient is bencyclan. The drug has no analogues. It must be taken one tablet 3 times a day.

Do not prescribe the drug for myocardial infarction. It is contraindicated in people under the age of 18, as well as in patients with epilepsy and hyperthyroidism.

The advantages of the drug include the rapid provision of an analgesic effect. It can be used by patients suffering from cholecystitis and gallstone disease. The drug is prescribed for people who have undergone surgery for the removal of the gallbladder and for dyskinesia of the sphincter of Oddi.

The downside of Galidor is its high cost. For a package of 50 tablets, you will need to pay 550 rubles. In addition, the drug can not be used to treat pregnant and lactating women, as well as with liver failure.

Buscopan

Buscopan
Buscopan

The main active ingredient is hyoscine. The drug has no analogues. It is not prescribed for urolithiasis, atherosclerosis and glaucoma.

The advantages of the drug include its pronounced antispasmodic effect (occurs 15 minutes after ingestion) and a decrease in the production of digestive secretions, which is very important for choleretic drugs. In this case, Buscopan does not affect the central nervous system.

The only drawback of the drug is its high cost. It varies in the range of 360-380 rubles.

List of cholelitis

Drugs from this drug group are used to prevent the formation of stones in the gallbladder, as they reduce the concentration of cholesterol in bile. They can also be used to dissolve small stones.

Cholelitis includes:

  • Ursosan.
  • Ursofalk.
  • Ursodeoxycholic acid.
  • Ursodez.
  • Greenterol.
  • Urdoks.

The drug with the lowest cost is Ursodeoxycholic acid (600 rubles for 50 tablets). The most expensive drug is Ursofalk (915 rubles for 50 tablets).

Cholelitics are produced in capsule form. The doctor determines the daily dose. It depends on the patient's weight and the presence of stones in the body.

Contraindications to taking cholelitics are: liver inflammation, inflammation of the gallbladder and bile ducts, pregnancy, lactation, calcium stones, biliary colic.

Choleretic herbal preparations

Plant-based choleretics

Drug name Composition and analogues How to use Contraindications Cons and pros
Flamin Basis: immortelle. The analogue is immortelle herb. One tablet three times daily before meals. Presence of stones larger than 10 mm, allergic reactions, age up to 3 years, mechanical jaundice. Pros: two forms of release with different prices (granules cost 280 rubles, and tablets 180 rubles), complex effect (antispasmodic, wound healing, antibacterial, choleretic, cholekinetic). Cons: there is no possibility to take the drug in patients with cholelithiasis and obturbatory jaundice.
Tanacehol Base: tansy extract. Analog - Tansy flowers for brewing and tansy flowers in granules. One or two tablets three times a day 20 minutes before meals Allergic reactions. Pros: low cost (30 rubles), quick antispasmodic effect, no side effects, except for allergic reactions. Cons: the drug should not be prescribed to patients with gallstone disease.
Berberis Homaccord Base: barberry in the form of drops. Analogs - Berberis vulgaris in granules. 10 drops, three times a day 20 minutes before meals or 60 minutes after meals Carrying a baby. Pros: the ability to eliminate inflammation in the gallbladder, no contraindications, except for breastfeeding. Cons: high price for the drug (550 rubles), the need for complex treatment.
Holosas Base: rosehip extract (syrup). Analogue - Rosehip syrup, rosehip fruits, Rosehip with vitamin C in syrup A teaspoon, 2 or 3 times a day. Allergic reactions and gallstone disease. Pros: affordable price (from 70 to 120 rubles), saturation of the body with vitamins, increased immunity, removal of inflammation. Cons: the drug can only be used in a complex scheme with other drugs.
Hofitol Base: artichoke extract. Analog - Artichoke Extract. The presence of stones in the gallbladder, liver and kidney damage in the acute stage, acute inflammation of the biliary tract and urinary tract. Pros: pronounced choleretic effect, normalization of liver function, saturation of the body with B vitamins and vitamin C. Cons: high cost of the drug (from 120 to 300 rubles),
Urolesan Ingredients: choleretic herbs. Analog - Holagol. The drug is applied to refined sugar in the amount of 8 drops and taken 3 times a day. Presence of stones more than 3 mm, allergic reactions. Pros: two forms of release (drops and capsules) Cons: high cost (310-350 rubles), the presence of contraindications for use, the inability to take the drug in the acute phase of the disease.
Valerian tablets Base: Valerian extract. Analog - Valerian in tincture 1-2 tablets 3-4 times a day. Individual intolerance to the drug. Pros: low cost, which starts from 45 rubles, the drug has an antispasmodic and choleretic effect. Cons: as an independent remedy, it has insufficient effectiveness, therefore, it is required to take it in combination with other medications.

Cholekinetics of plant origin

Cholekinetics of plant origin include preparations that contain any vegetable oils, but olive, sunflower and caraway oils have the greatest effect. In the same group, you can define: fennel (fruits), calamus (roots and rhizomes), barberry leaves, caraway seeds (fruits).

The drug Berberis-homaccord can also be attributed to herbal cholekinetics, since it has multiple effects, including normalizing the work of the bile ducts.

Cholespasmolytics of plant origin

The group of plant cholespasmolytics includes valerian, Holagol, as well as herbs such as: calendula, St. John's wort, tansy, arnica, turmeric root.

Choleretic drugs for the treatment of children

Choleretic drugs
Choleretic drugs

In childhood, the following choleretic drugs can be used:

  • From the age of 3, Holosas is prescribed.
  • From half a year, you can use Papaverine and Atropine, but under strict medical supervision.
  • From the age of 6, Hofitol, Flamin and Euphyllin are prescribed.
  • From 7 years old you can take Urolesan.
  • From 10 years old, Duspatalin is allowed to be admitted.

However, a specialist consultation is required before starting treatment.

The best choleretic drugs

Which drug is optimal should be determined by the doctor together with the patient.

Nevertheless, observations of recent years make it possible to identify the best choleretic agents, depending on their group:

  • Choleretics: Nikodin, Urolesan, Holosas, Tanacekhol.
  • Cholekinetics: Magnesium sulfate and sorbitol.
  • Cholespasmolytics: Buscopan and Duspatalin, since they have a targeted effect on the biliary tract. While Papaverine and No-shpa relieve spasm from smooth muscles of all organs.

Video: the president of the medical center for informing Sophia Dorinskaya about "safe choleretic drugs":

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The author of the article: Gorshenina Elena Ivanovna | Gastroenterologist

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Sharpening is carried out using tools such as a bar, a sharpener, a whetstone and a file. In order for the work to be done efficiently and not require significant physical effort, it is important to monitor the condition of all tools. First of all, you need to monitor their sharpening, which is carried out using tools such as a bar, a sharpener, a whetstone and a file. Sharpening tool This tool is designed to sharpen the blade of cutting tools. Sharpeners are produced in various